Saturday, May 8, 2010

Liver Diseases (Hepatic diseases)

  • Your liver is the largest organ inside your body. It is also one of the most important. The liver has many jobs, including changing food into energy and cleaning alcohol and poisons from the blood. Your liver also makes bile, a yellowish-green liquid that helps with digestion.

There are many kinds of liver diseases. Viruses cause some of them, like hepatitis A, hepatitis B and hepatitis C. Others can be the result of drugs, poisons or drinking too much alcohol. If the liver forms scar tissue because of an illness, it's called cirrhosis. Jaundice, or yellowing of the skin, can be one sign of liver disease.



  1. Like other parts of your body, cancer can affect the liver. You could also inherit a liver disease such as hemochromatosis.


Hepatitis :(Viral hepatitis)





  • Your liver helps your body digest food, store energy and remove poisons. Hepatitis is a swelling of the liver that makes it stop working well. It can lead to scarring, called cirrhosis, or to cancer.


  • Viruses cause most cases of hepatitis. The type of hepatitis is named for the virus that causes it; for example, hepatitis A, hepatitis B or hepatitis C. Drug or alcohol use can also lead to hepatitis. In other cases, your body mistakenly attacks its own tissues. You can help prevent some viral forms by getting a vaccine. Sometimes hepatitis goes away by itself. If it does not, it can be treated with drugs. Sometimes hepatitis lasts a lifetime.


  • Some people who have hepatitis have no symptoms. Others may have


  • Loss of appetite


  • Nausea and vomiting


  • Diarrhea


  • Dark-colored urine and pale bowel movements
    Stomach pain


  • Jaundice, yellowing of skin and eyes


hepatitis A:




  • Hepatitis A is one type of hepatitis - a liver disease - caused by the hepatitis A virus (HAV). The disease is spread primarily through food or water contaminated by stool from an infected person. You can get HAV from


  • Eating food prepared by someone with HAV who did not wash their hands after using the bathroom


  • Having anal/oral sex with someone with HAV


  • Not washing your hands after changing a diaper


  • Drinking contaminated water


  • HAV can cause swelling of the liver, but it rarely causes lasting damage. You may feel as if you have the flu, or you may have no symptoms at all. It usually gets better on its own after several weeks.


  • The hepatitis A vaccine can prevent HAV. Healthy habits also make a difference. Wash your hands thoroughly before preparing food, after using the toilet or after changing a diaper. International travelers should be careful about drinking tap water.


hepatitis B :( HBV)




  • Hepatitis B is one type of hepatitis – a liver disease- caused by the hepatitis B virus (HBV). Hepatitis B spreads by contact with an infected person's blood, semen or other body fluid. An infected woman can give hepatitis B to her baby at birth.


  • If you get HBV, you may feel as if you have the flu, or you may have no symptoms at all. A blood test can tell if you have it. HBV usually gets better on its own after a few months. If it does not get better, it is called chronic HBV, which lasts a lifetime. Chronic HBV can lead to scarring of the liver, liver failure or liver cancer.


  • There is a vaccine for HBV. It requires three shots. All babies should get the vaccine, but older children and adults can get it too. If you travel to countries where Hepatitis B is common, you should get the vaccine.


hepatitis C. (HCV):




  • Hepatitis C is one type of hepatitis - a liver disease - caused by the hepatitis C virus (HCV). It usually spreads through contact with infected blood. It can also spread through sex with an infected person and from mother to baby during childbirth.


  • Most people who are infected with hepatitis C don't have any symptoms for years. A blood test can tell if you have it. Usually, hepatitis C does not get better by itself. The infection can last a lifetime and may lead to scarring of the liver or liver cancer. Medicines sometimes help, but side effects can be a problem. Serious cases may need a liver transplant.


  • There is no vaccine for HCV.


Cirrhosis :(Hepatic fibrosis)




  • Cirrhosis is scarring of the liver. Scar tissue forms because of injury or long-term disease. Scar tissue cannot do what healthy liver tissue does - make protein, help fight infections, clean the blood, help digest food and store energy. Cirrhosis can lead to


  • Easy bruising or bleeding, or nosebleeds


  • Swelling of the abdomen or legs


  • Extra sensitivity to medicines


  • High blood pressure in the vein entering the liver


  • Enlarged veins in the esophagus and stomach


  • Kidney failure


  • About 5 percent of people with cirrhosis get liver cancer.


  • Cirrhosis has many causes. In the United States, the most common causes are chronic alcoholism and hepatitis. Nothing will make the scar tissue disappear, but treating the cause can keep it from getting worse. If too much scar tissue forms, you may need to consider a liver transplant.


Jaundice:(Icterus)




  • Jaundice causes your skin and the whites of your eyes to turn yellow. Too much bilirubin causes jaundice. Bilirubin is a yellow chemical in hemoglobin, the substance that carries oxygen in your red blood cells. As red blood cells break down, your body builds new cells to replace them. The old ones are processed by the liver. If the liver cannot handle the blood cells as they break down, bilirubin builds up in the body and your skin may look yellow.


  • Many healthy babies have some jaundice during the first week of life. It usually goes away. However, jaundice can happen at any age and may be a sign of a problem. Jaundice can happen for many reasons, such as:
    Blood diseases
    Genetic syndromes
    Liver diseases, such as hepatitis or cirrhosis
    Blockage of bile ducts
    Infections
    Medicines


Liver Cancer :(Hepatocellular carcinoma)




  • Your liver is the largest organ inside your body. It filters harmful substances from the blood, digests fats from food and stores the sugar that your body uses for energy. Primary liver cancer starts in the liver. Metastatic liver cancer starts somewhere else and spreads to your liver.


  • Risk factors for primary liver cancer include
    Having hepatitis
    Having cirrhosis, or scarring of liver
    Being male
    Low weight at birth


  • Symptoms can include a lump or pain on the right side of your abdomen and yellowing of the skin. However, you may not have symptoms and the cancer may not be found until it is advanced. This makes it harder to treat. Treatment options include surgery, radiation, chemotherapy or liver transplantation.


Hemochromatosis :(Iron overload disease)




  • Hemochromatosis is an inherited disease in which too much iron builds up in your body. It is one of the most common genetic diseases in the United States.


  • Iron is a mineral found in many foods. Your body normally absorbs about 10 percent of the iron in the food you eat. If you have hemochromatosis, you absorb more iron than you need. Your body has no natural way to get rid of the extra iron. It stores it in body tissues, especially the liver, heart and pancreas. The extra iron can damage your organs. Without treatment, it can cause your organs to fail.


  • The most common treatment is to remove some blood, just like when you donate blood. This is called therapeutic phlebotomy. Medicines may also help remove the extra iron. Your doctor might suggest some changes in your diet.

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