IMP

Hemochromatosis

Best Initial: Transferrin saturation 

Most Accurate: Liver biopsy 

Prognostic Indicator: Liver biopsy

(EASIER WAY TO REMEMBER)

IMP POINTS (EASIER WAY TO REMEMBER)

Indications for Erythropoietin:

1. Anemia due to chronic kidney disease

2. Anemia due to treatment for cancer when Hb less than 10  

3. Anemia due to Zidovudine use in HIV/AIDS

Increased risk of thrombosis when Hb >12

Contraindication: Lance Armstrong

IMP POINTS

Polyarteritis nodosa 

- every organ can be affected in the body, except the lung
- can be associated with hepatitis B

Symptoms:

- fever, malaise, weight loss, myalgias and arthralgia;

- GI: abdominal pain, bleeding, vomiting; Pain can be worsened by eating (mesenteric vasculitis);

- neurologic: mononeuritis multiplex; stroke in a young person!!!

- skin: purpura, petechiae, digital gangrene, livedo reticularis

Best initial test: ANGIOGRAPHY of renal, mesenteric or hepatic artery (aneurysmal dilatation)

Most accurate diagnostic test: Biopsy of symptomatic site

Treatment: Prednisone and Cyclophophamide and treat hep B

6)A 22-year-old man complains to his family physician of fatigue, night sweats, and a dry unproductive cough. Until the past few
months, he had apparently been in good health. Acomplete blood count (CBC) and differential blood count reveal that he is lymphopenic. X-ray examination reveals an interstitial pneumonia. Skin test reactions to a battery of materials are normal. Which of the
following should be the next step in evaluating this patient’s illness?

A. CH50 complement assay
B. chemotaxis assay
C. identification of the organism that is
causing the pneumonia
D. intracellular killing assay
E. nitroblue tetrazolium reduction assay

5)A 62-year-old woman with cardiac disease undergoes a pudendal nerve block to remove a tumor from the vulva. Fibers forming the
pudendal nerve originate from which of the following?
(A) L2–L4
(B) L3–L5
(C) L4, L5, S1
(D) S1–S3
(E) S2–S4

4)During a workup for infertility, a 34-year-oldman is noted to have a solid tumor in the anterior aspect of his right testis. What is the most likely diagnosis?
(A) Torsion of the testis
(B) Cyst of the epididymis
(C) Lipoma of the cord
(D) Cancer of the testis
(E) Epididymo-orchitis

3)A 35-year-old man presents with cough, haemoptysis and glomerulonephritis. His c-ANCA levels are elevated.

What is the most likely cause for these features?

a. Goodpasture’s syndrome 
b. Polyarteritis nodosa 
c. Wegener’s granulomatosis 
d. Microscopic polyangiitis